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MetroCream Drug Interactions

There are a few products that may cause problems when used in combination with MetroCream. Research has shown that the active ingredient in MetroCream may cause drug interactions with products like alcohol, lithium, and disulfiram. Some of these interactions may increase your risk for side effects, such as bleeding or hallucinations.

An Overview of Interactions With MetroCream

MetroCream® (metronidazole cream) may react with a few other medications. Some of the drugs that can interact with MetroCream include but are not limited to:
 
 

MetroCream Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when MetroCream is combined with any of the drugs listed above.
 
Alcohol
The standard recommendation is that people taking metronidazole products, including MetroCream, not drink alcohol. However, this type of interaction is probably unlikely to occur when metronidazole is applied to the skin, such as with MetroCream, although this is not known for sure. In addition, there is some uncertainty about the validity of this interaction (see Metronidazole and Alcohol).
 
Amprenavir
Combining MetroCream with amprenavir oral solution (but not the other forms of amprenavir) can cause dangerous interactions with metronidazole (the active ingredient in MetroCream). It is unclear whether this interaction applies to the skin formulations of metronidazole such as MetroCream, as only a small amount of the medication is absorbed from the skin into the bloodstream. Check with your healthcare provider before using these medications together.

MetroCream Medication Information

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