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Mirvaso is a medication prescribed to treat rosacea. It comes as a gel that is applied to the skin once daily. This medicine works by constricting the blood vessels in the face, which helps reduce redness almost immediately. Side effects are possible and include redness, flushing, and a burning sensation.

What Is Mirvaso?

Mirvaso® (brimonidine gel) is a prescription rosacea medication. It comes as a gel that is applied to the skin once a day. It specifically addresses the redness that most people with rosacea experience.
(Click Mirvaso Uses for more information on this topic, including possible off-label uses.)

Who Makes It?

This medication is made by Galderma Laboratories.

How Does Mirvaso Work?

Mirvaso is an alpha-2 adrenergic agonist. It works by activating alpha-2 adrenergic receptors, causing blood vessels of the face to constrict (narrow). This constriction causes an immediate but temporary reduction in redness.  

Clinical Effects

In one clinical study, 22 percent to 31 percent of people who applied Mirvaso had a 2-grade improvement on both a self-assessment and a professional assessment of their rosacea symptoms. In comparison, 9 percent to 11 percent of people who applied a placebo gel (with no active ingredient) had a similar improvement.
Improvements are seen immediately in the first day, and the effects typically last at least 12 hours.

When and How to Use It

Some general considerations to keep in mind during treatment with Mirvaso include the following:
  • Apply this medication to the face once daily.
  • Dot a pea-sized amount on your forehead, each cheek, nose, and chin, and then gently spread it in a thin layer over the entire face, avoiding the eyes and lips.
  • Let it dry before applying any cosmetics or other facial products.
  • Wash your hands after applying Mirvaso.
  • For the medication to work properly, it must be used as prescribed.  

Mirvaso Gel Information

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